Abstract

Objective: This study aims to show the feasibility, safety, and efficacy of the Nit-Occlud® Lê VSD (PFM coil) in the treatment of peri membranous ventricular septal defects. Background: Most ventricular septal defects are closed surgically, while less invasive transcatheter treatment using closure devices is an alternative. Device-based closure is reported to be associated with the risk of complete atrioventricular block and impingement on the tricuspid valve. However, the PFM coil represents a less invasive alternative to surgical closure, offering fewer complications for closing peri membranous defects. Methods: This is a single-center, retrospective study which included all patients diagnosed with peri membranous ventricular septal defects who underwent transcatheter closure using the Nit-Occlud® Lê VSD (PFM coil) from January 2015 to December 2020, at Prince Sultan Cardiac Center (PSCC) Riyadh, Kingdom of Saudi Arabia. Results: Transcatheter VSD closure with PFM coil was performed in 11 patients. The mean age was 10.27±5.50 years and body mass index was18.30±6.32 kg/m2. Eight cases had a small residual VSD at the 3-month after procedure, and only two of these patients (20% of the total) had residual VSD after 5 years. Five patients had mild tricuspid valve regurgitation (TR) at 3 months which improved in 2 of them at 5 years. One patient had moderate TR before closure, which improved to a mild degree. No complications occurred. Conclusion: The Nit-Occlud® Lê VSD coil offers the possibility of an effective and safe treatment approach for patients with peri membranous ventricular septal defects. The potential for TR improvement with this procedure needs to be tested with larger prospective studies. The uneventful completion of the procedure in this cohort is promising and encouraging for future use.

Keywords

  • Ventricular septal defect Interventional therapy PFM coil Residual shunt Tricuspid valve regurgitati

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